Here's a suggestive itinerary for a 2-night holiday in Lisbon from the UK:

Day 1: Arrival in Lisbon

• Fly from the UK to Lisbon, the vibrant capital city of Portugal.
• Arrive in Lisbon and transfer to your hotel.
• Spend the afternoon exploring the historic neighborhood of Alfama, known for its narrow streets, colorful buildings, and Fado music.
• Visit the Lisbon Cathedral, São Jorge Castle, and enjoy panoramic views of the city from the castle's viewpoints.
• In the evening, dine at a traditional Portuguese restaurant and sample local delicacies.

Day 2: Lisbon City Exploration

• Start the day with a visit to Belém, a historical district of Lisbon.
• Explore the iconic Belém Tower, a UNESCO World Heritage site.
• Visit the stunning Jerónimos Monastery, a masterpiece of Manueline architecture.
• Don't miss the opportunity to taste the famous pastel de nata (custard tart) at the renowned Pastéis de Belém bakery.
• Afterward, head to downtown Lisbon, Baixa, and take a stroll along the elegant Avenida da Liberdade.
• Explore the charming squares of Rossio and Praça do Comércio.
• Ride the historic Tram 28, which takes you through the narrow streets of the city.
• In the evening, enjoy the vibrant nightlife of Lisbon in the Bairro Alto district, known for its bars, live music, and lively atmosphere.

Day 3: Departure

• On your last day in Lisbon, visit the trendy neighborhood of Chiado, known for its boutiques, theaters, and cafés.
• Explore the unique LX Factory, a creative hub filled with art galleries, shops, and trendy restaurants.
• Take a stroll along the picturesque streets of the bohemian district of Bairro Alto.
• Enjoy a leisurely lunch at a traditional Portuguese restaurant.
• Depending on your flight time, you may have some free time for last-minute shopping or exploring before transferring to the airport for your return flight to the UK.

Please note that this itinerary provides a general framework for your 2-night holiday in Lisbon, and you can adjust it based on your interests and the specific attractions you wish to visit. Lisbon is a city full of charm, history, and delicious food, so take the opportunity to immerse yourself in its unique atmosphere.